Agave has been a mainstay of culture in the Americas for millenia: food, drink, tool, spirit, utilitarian, sacred. Adaptations to aridity represented by both agave and people hold critical insights into how to live in the desert. This lecture series looks closely at these adaptations and the reciprocal relationship between this desert plant and people. Through presentations, roundtable discussions, tastings, and art we will collectively reconnect to the importance of agave, how this relationship in threatened by climate change and our actions, and also how a resilient future is embedded in the heart of a plant.